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RECRUITING
NCT05574244
NA

Comparison of Functional Outcomes of Ejaculation-preserving Partial Trans Urethral Resection of the Prostate With Complete Trans Urethral Resection of the Prostate for Benign Prostatic Obstruction

Sponsor: University Hospital, Bordeaux

View on ClinicalTrials.gov

Summary

It has been demonstrated that sexual activity was common in the majority of men over 50 years old and was an important component of overall quality of life (QoL). Ejaculatory dysfunction (EjD) is the most common side effect of surgical treatment of benign prostatic obstruction (BPO). It has been considered for decades to be an inevitable consequence of restoring micturition comfort. EjD can have a substantial deleterious effect on the QoL of men with previously maintained regular sexual activity, inducing decreased orgasmic intensity and increased levels of anxiety and depression. A better understanding of the physiology of ejaculation has enabled the emergence of modified surgical techniques that aim to preserve antegrade ejaculation. Our hypothesis is that conservation of ejaculation can be achieved by modified surgical procedures without compromising functional outcomes.

Key Details

Gender

MALE

Age Range

40 Years - Any

Study Type

INTERVENTIONAL

Enrollment

336

Start Date

2022-09-29

Completion Date

2029-03-31

Last Updated

2026-04-09

Healthy Volunteers

No

Interventions

PROCEDURE

Partial surgery preserving the prostatic apex

Partial Endoscopic resection of prostate to conserve apex

PROCEDURE

Conventional endoscopic prostatic surgery

Endoscopic resection of prostate.

Locations (17)

CH Pays d'Aix

Aix-en-Provence, France

CHU Angers

Angers, France

Centre Hospitalier Universitaire de Bordeaux

Bordeaux, France

CHU Mondor

Créteil, France

Hôpital Claude Huriez

Lille, France

CHU de Limoges

Limoges, France

Hôpital Nord Marseille

Marseille, France

Polyclinique Saint George

Nice, France

Hôpital cochin

Paris, France

Hôpital Prive Francheville

Périgueux, France

Hôpital Lyon Sud HCl Bât.3C Centre Hospitalier Lyon Sud

Pierre-Bénite, France

Hôpital Privé des Côtes D'Armor

Plérin, France

CHU de Reims- Hôpital Robert Debré

Rennes, France

CHU de Rennes

Rennes, France

Clinique Pasteur

Toulouse, France

CHRU Hôpitaux de tours

Tours, France

Hopital Privé de Versailles, Clinique des Franciscaines

Versailles, France