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Hemodynamic Stability in Septic Shock Patients Undergoing Continuous Renal Replacement Therapy With oXiris Membrane
Sponsor: Seoul National University Hospital
Summary
The new adsorbing membrane for continuous renal replacement therapy (CRRT), oXiris, can reduce plasma cytokines and endotoxins in septic shock patients with severe acute kidney injury, compared with standard membranes. However, its hemodynamic stability or benefits have not been thoroughly evaluated although this is reasonable.
Official title: Real-time Monitoring of Hemodynamic Stability in Septic Shock Patients Undergoing Continuous Renal Replacement Therapy: Propensity Score-matched Comparison Between oXiris and Polysulfone Membranes
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
98
Start Date
2024-01-01
Completion Date
2026-12-31
Last Updated
2025-05-15
Healthy Volunteers
No
Conditions
Interventions
oXiris membrane
Perform continuous renal replacement therapy with oXiris membrane
Polysulfone membrane
Perform continuous renal replacement therapy with polysulfone membrane
Locations (1)
Seoul National University Hospital
Seoul, South Korea