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RECRUITING
NCT05575024

Hemodynamic Stability in Septic Shock Patients Undergoing Continuous Renal Replacement Therapy With oXiris Membrane

Sponsor: Seoul National University Hospital

View on ClinicalTrials.gov

Summary

The new adsorbing membrane for continuous renal replacement therapy (CRRT), oXiris, can reduce plasma cytokines and endotoxins in septic shock patients with severe acute kidney injury, compared with standard membranes. However, its hemodynamic stability or benefits have not been thoroughly evaluated although this is reasonable.

Official title: Real-time Monitoring of Hemodynamic Stability in Septic Shock Patients Undergoing Continuous Renal Replacement Therapy: Propensity Score-matched Comparison Between oXiris and Polysulfone Membranes

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

98

Start Date

2024-01-01

Completion Date

2026-12-31

Last Updated

2025-05-15

Healthy Volunteers

No

Interventions

DEVICE

oXiris membrane

Perform continuous renal replacement therapy with oXiris membrane

DEVICE

Polysulfone membrane

Perform continuous renal replacement therapy with polysulfone membrane

Locations (1)

Seoul National University Hospital

Seoul, South Korea