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Collagen Matrix + rhPDGF-BB vs Connective Tissue Graft for the Treatment of Peri-implant Soft Tissue Dehiscences
Sponsor: Harvard Medical School (HMS and HSDM)
Summary
The study aims at comparing two different approaches for the treatment of implant esthetic complications (peri-implant soft tissue dehiscences): autogenous connective tissue graft vs collagen matrix + recombinant human platelet derived growth factor-BB
Official title: Xenogeneic Collagen Matrix Loaded With rhPDGF-BB vs Autogenous Connective Tissue Graft for the Treatment of Peri-implant Soft Tissue Dehiscences: A Randomized, Controlled, Clinical, Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
28
Start Date
2023-01-04
Completion Date
2025-10-21
Last Updated
2025-04-10
Healthy Volunteers
Yes
Conditions
Interventions
Prosthetic-surgical approach + autogenous graft
Coronally advanced flap with an autogenous graft (CTG)
Prosthetic-surgical approach + graft substitute
Coronally advanced flap with a graft substitute (collagen matrix and rhPDGF-BB)
Locations (1)
Harvard School of Dental Medicine
Boston, Massachusetts, United States