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Dexmedetomidine in Off Pump Coronary Artery Bypass Grafting
Sponsor: Suez Canal University
Summary
the study will assess the impact of intraoperative dexmedetomidine infusion on myocardial performance by investigating the left ventricular (LV) systolic and diastolic function and right ventricular (RV) fraction area change (which reflect RV systolic function) using two-dimensional trans-esophageal echocardiography (TEE) in patients undergoing elective first-time isolated off-pump coronary artery bypass (OPCAB) grafting. LV Systolic function will be measured by the TEE via the fractional area change, fraction shortening, and ejection fraction.
Official title: Echocardiographic Evaluation of the Effect of Dexmedetomidine Infusion as an Adjuvant to General Anesthesia in Off-pump Coronary Artery Bypass Grafting
Key Details
Gender
All
Age Range
21 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
36
Start Date
2022-11-01
Completion Date
2024-09-30
Last Updated
2026-05-26
Healthy Volunteers
No
Conditions
Interventions
Dexmedetomidine
infusion of dexmedetomidine during the off pump coronary artery bypass grafting surgery
normal saline
infusion of normal saline during the off pump coronary artery bypass grafting surgery
Locations (1)
Faculty of Medicine, Suez Canal University
Ismailia, Egypt