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RECRUITING
NCT05580614
NA

Paired tVNS With ERP in OCD

Sponsor: University of Florida

View on ClinicalTrials.gov

Summary

In the proposed investigation, the investigator will develop pilot data for the use of tVNS (transcutaneous vagal nerve stimulation) to enhance efficacy of exposure and response prevention therapy (ERP) to improve treatment success in patients with OCD. This data will include tolerability information from therapists and patients with OCD, effect sizes on real world clinical outcomes for the combinatory treatment, and mechanistic data on brain changes associated with treatment.

Official title: Pairing tVNS and Exposure and Response Prevention to Improve Symptoms of OCD

Key Details

Gender

All

Age Range

18 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

56

Start Date

2022-06-27

Completion Date

2026-08-31

Last Updated

2025-10-27

Healthy Volunteers

No

Conditions

Interventions

DEVICE

Sham

MRI (Magnetic Resonance Imaging) paired ERP/Sham YBOCs(Yale-Brown Obsessive Compulsive Scale) (4,8,12) OCI-R (every other session). YBOCs and OCI-R will also be administered at intake and 4 weeks post treatment.

DEVICE

tVNS

MRI (Magnetic Resonance Imaging) paired ERP/tVNS YBOC's (Yale-Brown Obsessive Compulsive Scale) (4, 8, 12) OCI-R (every other session). YBOCs and OCI-R will also be administered at intake and 4 weeks post treatment.

Locations (1)

University of Florida

Gainesville, Florida, United States