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Experience With Topical Acne Treatment
Sponsor: Wake Forest University Health Sciences
Summary
Acne is a chronic condition that typically requires the use of multiple medications.1 Medication adherence is especially challenging for patients with chronic diseases and often decreases over time, especially for those using topical medications.1 Nonadherence can result in multiple negative effects including treatment failure, increased healthcare costs, and decreased quality of life. Primary nonadherence refers to problems acquiring and starting treatment. Challenges to this form of nonadherence include a lack of knowledge, misunderstanding of usage, poor communication with provider, increased cost, and fear of side effects.2 Secondary nonadherence refers to when the patient does not use the medication as prescribed. Hurdles to secondary nonadherence include delayed results, increased complexity of treatment plan, adverse effects, busy lifestyle, and inconvenience.2
Official title: Factors Affecting Medication Adherence to Topical Acne Medications: a Single-center, Prospective Study Evaluating the Adherence and Patient Satisfaction to Single and Multiple Topical Acne Medications
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
72
Start Date
2024-02-15
Completion Date
2026-11
Last Updated
2025-12-24
Healthy Volunteers
No
Conditions
Interventions
clindamycin phosphate 1.2%/adapalene 0.15%/BPO 3.1% gel
Single topical treatment to be applied daily to area affected once daily.
adapalene 0.3%/BPO 2.5% gel and compounded clindamycin phosphate 1.2% gel
Two topical treatments to be applied to area affected once daily.
Compounded BPO 2.5% gel, adapalene 0.1% gel, and compounded clindamycin phosphate 1.2% gel
Three topical treatments to be applied to area affected once daily.
Locations (1)
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States