Clinical Research Directory

Inclusion Criteria: * Male or female Exclusion Criteria: * Younger than 25 years old and older than 80 years old at the beginning of the intervention. * Body mass index less than 18 or greater than 40 kg/m2. * Blood pressure greater than 160/100 mm Hg or use of medication to treat hypertension for less than 6 months. * Use of medications that will affect the study outcomes, including cholesterol lowering medications. * Pregnant women, lactating women, women who plan to become pregnant during the study, or women who have given birth during the previous 12 months. * Fasting blood glucose over 125 mg/dL or type 2 diabetes requiring medication. * Body weight change of 10% in the past 3 months. * History of bariatric or other gastrointestinal surgery that would affect digestion. * History or presence of diabetes, kidney disease, liver disease, certain cancers, gout, hyperthyroidism, untreated or unstable hypothyroidism, gastrointestinal disease, pancreatic disease, other metabolic diseases, or malabsorption syndromes. * Smokers, vapers, or other tobacco users (within 6 months prior to the start of the study). * Use of an antibiotic within 1 month of the start of the study or during the study. * Plans to have a colonoscopy during the study. * Allergy to any food included in the study menus. * Unable or unwilling to give informed consent or communicate with study staff. * Self-report of alcohol or substance abuse within the past 12 months and/or current acute treatment or rehabilitation program for these problems (long-term participation in Alcoholics Anonymous is not an exclusion). * Other medical, psychiatric, or behavioral factors that in the judgment of the Principal Investigator may interfere with study participation or the ability to follow the intervention protocol.