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Dupilumab in Adolescent and Adult Skin of Color Participants: Open-label Moderate-to-severe Eczema Trial
Sponsor: Regeneron Pharmaceuticals
Summary
The study is focused on skin of color participants who have moderate-to-severe atopic dermatitis. Atopic dermatitis, also referred to as eczema, is a condition that causes the skin to become itchy, dry, and cracked. From the previous studies on the study drug, it is seen that the study drug has an acceptable safety and effectiveness in participants with atopic dermatitis. The aim of this study is to get additional information on the safety and effectiveness of the study drug, particularly the information on aspects of atopic dermatitis in skin of color participants. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug * How much study drug is in your blood at different times * How much the study drug improves quality of life and mental health
Official title: An Open-Label Single-Arm Study of Dupilumab in Adolescent and Adult Skin of Color Patients With Moderate-to-Severe Atopic Dermatitis
Key Details
Gender
All
Age Range
12 Years - Any
Study Type
INTERVENTIONAL
Enrollment
124
Start Date
2023-01-11
Completion Date
2024-11-14
Last Updated
2026-05-27
Healthy Volunteers
No
Interventions
dupilumab
Administered by subcutaneous (SC) injection once every 2 weeks (Q2W) following a loading dose
Topical emollient (moisturizer)
Moisturizer should be applied twice daily, as per physician's recommendation, as defined in protocol.
Locations (30)
Total Skin & Beauty Dermatology Center
Birmingham, Alabama, United States
The University Of Alabama At Birmingham
Birmingham, Alabama, United States
C2 Research Center, LLC
Montgomery, Alabama, United States
Center for Dermatology Clinical Research, inc.
Fremont, California, United States
UCSD/ Rady Children's Hospital
San Diego, California, United States
UCSF
San Francisco, California, United States
SF Research Institute
San Francisco, California, United States
University of Miami Miller School of Medicine
Miami, Florida, United States
Skin and Cancer Associates, LLP
Miami, Florida, United States
Century Research LLC
Miami, Florida, United States
Advanced Medical Research PC
Atlanta, Georgia, United States
Atlanta Biomedical Clinical Research LLC
Atlanta, Georgia, United States
Northwestern Memorial Hospital
Chicago, Illinois, United States
Callender Dermatology and Cosmetic Center
Glenn Dale, Maryland, United States
Dermatology and Skin Cancer Specialists, LLC dba US Dermatology Partners
Rockville, Maryland, United States
Wayne State University Physician Group Dermatology
Dearborn, Michigan, United States
Revival Research Institute , LLC
Troy, Michigan, United States
Washington University School of Medicine
St Louis, Missouri, United States
Rao Dermatology
Atlantic Highlands, New Jersey, United States
SUNY Downstate Medical Center
Brooklyn, New York, United States
NYC Health + Hospital , Elmhurst Hospital Center
Elmhurst, New York, United States
Markowitz Medical
New York, New York, United States
Philip Fried, MD PLLC
The Bronx, New York, United States
Duke University Medical Center
Durham, North Carolina, United States
Oregon Health & Science University
Portland, Oregon, United States
National Allergy and Asthma Research, LLC.
North Charleston, South Carolina, United States
Center for Clinical Studies, LTD.LLP
Houston, Texas, United States
Heights Dermatology & Aesthetic Center - Heights Location
Houston, Texas, United States
RFSA Dermatology
San Antonio, Texas, United States
Texas Dermatology and Laser Specialists
San Antonio, Texas, United States