Clinical Research Directory

Case group (CSDH group) Inclusion Criteria: * Patients (18 years to 90 years) presenting with clinical symptoms and neurological deficits of CSDH. * CSDH verified on cranial computed tomography or magnetic resonance imaging. * Written informed consent from patients or their next of kin according to the patient's cognitive status. Control group (Healthy group) Inclusion Criteria: * non-CSDH patients (18 years to 90 years) with matched age and gender. * Written informed consent from patients or their next of kin according to the patient's cognitive status. Exclusion Criteria for both case and control group: * Previous intracranial surgery for any neurological disorders but chronic subdural hematoma before. * CSDH turned from acute subdural hematoma. * Existing malignant tumors, poor medication condition or severe comorbidity. * Difficulty in feeding requiring long-term enteral or parenteral nutrition support. * Dietary and nutritional survey is estimated to be completed difficultly. * Reproductive-age women without verified negative pregnancy testing. * Participating in other research.