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The Impact of Product Formulation on the Pharmacokinetics and Pharmacodynamics of Cannabis Edibles
Sponsor: Johns Hopkins University
Summary
This study will examine the pharmacokinetics and pharmacodynamics of delta-9-tetrahydrocannabinol (THC)-infused chocolates, gummies, and drinks. Healthy adults (N=40) will complete 9 drug administration sessions, including an overnight stay prior to each session. Participants will consume THC containing products in a fasted state; following drug administration, the participants will complete cognitive and psychomotor tasks, subjective assessments, have blood collected, and vital signs monitored.
Key Details
Gender
All
Age Range
21 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2024-07-10
Completion Date
2027-01
Last Updated
2025-04-18
Healthy Volunteers
Yes
Conditions
Interventions
Cannabis
Cannabis will be orally ingested
Placebo
Placebo will be orally ingested
Locations (1)
Johns Hopkins Behavioral Pharmacology Research Unit
Baltimore, Maryland, United States