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Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers
Sponsor: University of Calgary
Summary
Local anesthetic resistance is commonly reported by patients with EDS. However, there are no objective data on the occurrence of local anesthetic resistance in EDS patients and in healthy volunteers. The investigators propose to collect such objective data on the frequency of drug resistance and whether any problems with local anesthesia are due to initial ineffectiveness or due to its effects dissipating too soon.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
155
Start Date
2022-11-10
Completion Date
2027-06
Last Updated
2024-12-18
Healthy Volunteers
Yes
Conditions
Interventions
0.9% Sodium Chloride Injection
All participants will be injected subcutaneously with a single 0.5ml dose
Lidocaine Injection 2%
All participants will be injected subcutaneously with a single 0.5ml dose
Locations (1)
Cardiovascular Autonomic Research Lab, University of Calgary
Calgary, Alberta, Canada