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RECRUITING
NCT05605639
PHASE4

Phrenic Nerve Infiltration in Neck Pain

Sponsor: University of Seville

View on ClinicalTrials.gov

Summary

Neck pain frequently present comorbidities in peridiaphragmatic organs. The innervation of these organs include the phrenic nerve. It is known that peridiaphragmatic organs trigger referred pain in the neck area. As well, previous studies have shown that visceral disorders increase sensitization in somatic tissues. This study aims to analyze the ability of phrenic nerve infiltration to diminish sensitization and improve neck symptoms in the absence of neurological, traumatic or infectious pathology that justifies the pain, by means of a randomized controlled trial.

Official title: Phrenic Afferences In Organic and Metabolic Illness: Central Sensitization

Key Details

Gender

All

Age Range

18 Years - 64 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2022-11-17

Completion Date

2025-07

Last Updated

2024-12-11

Healthy Volunteers

No

Interventions

DRUG

Bupivacaine

The experimental intervention will consist of ultrasound-guided anesthetic blockade of the phrenic nerve at the laterocervical supraclavicular level with 1 ml of lidocaine without vasoconstrictor 2% to infiltrate the skin and 3ml of bupivacaine without vasoconstrictor 0.25% for neural blockade, making the local anesthetic surround the nerve between the anterior scalene muscle and the sternocleidomastoid muscle.

OTHER

Placebo (physiological saline serum infiltration)

The placebo intervention will be similar in relation to 2% lidocaine without vasoconstrictor for the skin, but an ultrasound-guided puncture will be performed at the level of the subcutaneous cellular tissue by injecting 3 ml of physiological saline.

Locations (2)

Nacho Navarro Fisioterapia

Dos Hermanas, Seville, Spain

Crux Roxa

Seville, Spain