Clinical Research Directory
Browse clinical research sites, groups, and studies.
Effect of Hormones on Frequency of Headache and Brain Structure and Function in Puberty
Sponsor: University of Colorado, Denver
Summary
With a rising population of transgender adults and youth, there is a need for more research to meet the needs of this community. Transfemale (MTF) youth (male sex, female gender identity) who begin clinical Gender Affirming Hormone Therapy (GAHT) with estrogen may be at a higher risk for headache since estrogen has been linked to headache in cisgender females (female sex, female gender identity). This research hopes to learn more about headache in MTF youth.
Key Details
Gender
All
Age Range
9 Years - 20 Years
Study Type
OBSERVATIONAL
Enrollment
140
Start Date
2021-12-14
Completion Date
2026-06-30
Last Updated
2025-07-04
Healthy Volunteers
Yes
Conditions
Interventions
Clinical estrogen therapy
No research interventions will be used as a part of the study since the research is observational. Estrogen treatment will be prescribed and followed by participant's clinical physician.
Locations (1)
Children's Hospital Colorado
Aurora, Colorado, United States