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Integration of Hypertension Management in HIV Care in Uganda
Sponsor: Infectious Diseases Research Collaboration, Uganda
Summary
Effective, cost-effective, scalable, sustainable, and equitable implementation strategies to improve care for people living with HIV and co-morbid hypertension in sub-Saharan Africa are urgently needed. Our study will compare the effectiveness, scalability, and cost-effectiveness of a lower-resource intensive vs. a higher resource intensive strategy to integrate hypertension care into HIV clinics in Uganda.
Official title: PULESA Uganda: Strengthening the Blood Pressure Care and Treatment Cascade for Ugandans Living With HIV-ImpLEmentation Strategies to SAve Lives
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
87421
Start Date
2023-02-06
Completion Date
2025-10-03
Last Updated
2026-07-23
Healthy Volunteers
No
Conditions
Interventions
HTN-BASIC
The HTN-BASIC intervention will consist of providing consistent access to diagnostic equipment and evidence-based antihypertensive drugs at no cost to the hypertensive patients. Access to a consistent supply of three anti-hypertensive drugs (amlodipine 5, 10mg; valsartan 80, 160mg; and hydrochlorothiazide 12.5, 25mg) will be supplied to each clinic in the trial.
HTN-PLUS
In addition to receiving all the components of HTN-BASIC, HTN-PLUS sites will receive an enhanced, more human-resource intensive package of interventions that have been developed in consultation with key stakeholders during our human-centered design phase. The intervention components will include four broad categories- (1) hypertension training, (2) differentiated service delivery and (3) remote patient monitoring for hypertension and (4) Performance Improvement Program. Uptake of all components will be assessed on a monthly basis during the intervention period. These interventions will by nature cost more, and so cost data will be rigorously collected as well.
Locations (16)
Butabika
Kampala, Uganda
Kawala
Kampala, Uganda
Kisenyi
Kampala, Uganda
Kitebi
Kampala, Uganda
Komamboga
Kampala, Uganda
Mengo Hospital
Kampala, Uganda
Naguru
Kampala, Uganda
Nsambya
Kampala, Uganda
Bweyogerere
Wakiso, Uganda
Entebbe RRH
Wakiso, Uganda
Kakiri
Wakiso, Uganda
Kawanda
Wakiso, Uganda
Nakawuka HCIII
Wakiso, Uganda
Nsangi HCIII
Wakiso, Uganda
Nurture Africa
Wakiso, Uganda
Saidina
Wakiso, Uganda