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Efficacy of Preconditioned Adipose-Derived Stem Cells in Fat Grafting
Sponsor: University of the Punjab
Summary
The aim of this study is to evaluate the comparison of therapeutic potential of curcumin preconditioned adipose derived stem cells (ASCs) enrichment fat grafting, naïve ASCs enrichment fat grafting and conventional fat grafting to correct facial contour deformities that cause aesthetic complications in patients.
Official title: Supplementation of Autologous Fat Grafts with Curcumin Preconditioned Adipose-Derived Stem Cells in the Treatment of Facial Contour Deformities
Key Details
Gender
All
Age Range
18 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
24
Start Date
2020-11-20
Completion Date
2025-12
Last Updated
2024-12-31
Healthy Volunteers
No
Interventions
Cultured ASCs enrichment fat grafting
Patients will undergo conventional fat harvesting. Harvested fat will be mixed with cultured ASCs and grafted into recipient site with 1,00,000 cells/ml injected fat
Curcumin-preconditioned ASCs enrichment fat grafting
Patients will undergo conventional fat harvesting. Harvested fat will be mixed with cultured ASCs preconditioned with curcumin and grafted into recipient site with 1,00,000 cells/ml injected fat
Conventional fat grafting
Patients will undergo conventional fat harvesting and grafting of fat into recipient site
Locations (1)
Stem Cell Laboratory, Jinnah Burn and Reconstructive Surgery Center (JB&RSC)
Lahore, Punjab Province, Pakistan