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Precision Analgesia for Cardiac Surgery
Sponsor: Kathirvel Subramaniam
Summary
The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research. This research focuses on two of the most commonly used oral opioid analgesics, oxycodone, and methadone in elderly adults undergoing cardiac surgery.
Official title: Precision Perioperative Methadone Use in Adult Cardiac Surgical Patients to Reduce Opioid Use Adverse Effects While Improving Analgesia and Outcomes
Key Details
Gender
All
Age Range
60 Years - 110 Years
Study Type
OBSERVATIONAL
Enrollment
400
Start Date
2026-04-01
Completion Date
2026-12-01
Last Updated
2025-09-18
Healthy Volunteers
No
Conditions
Locations (1)
UPMC Presbyterian Hospital
Pittsburgh, Pennsylvania, United States