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Improve Outcomes for Older Allogeneic Transplant Recipients
Sponsor: Abramson Cancer Center at Penn Medicine
Summary
This is an interventional pilot study to determine whether implementation of a supervised exercise program can improve outcomes in subjects undergoing allogeneic HCT. The primary objective is to determine feasibility. Up to 60-72 evaluable subjects will be enrolled. Evaluable subjects are defined as those participating in the exercise intervention.
Official title: Intervening on Frailty to Improve Outcomes for Older Allogeneic Transplant Recipients
Key Details
Gender
All
Age Range
60 Years - Any
Study Type
INTERVENTIONAL
Enrollment
72
Start Date
2023-02-15
Completion Date
2031-06-01
Last Updated
2025-12-10
Healthy Volunteers
No
Conditions
Interventions
Exercise Program (Cohort A Prehab)
Pre-frail and frail potential HCT recipients 60 years and older will participate in a supervised exercise program from the time of enrollment up until HCT admission. Exercise compliance will be measured in part through physical activity trackers.from time of discharge from HCT until day +100 post-HCT. All HCT recipients 60 years and older will participate in a supervised exercise program from the time of discharge from HCT admission until day +100 post-HCT. Exercise compliance will be measured in part through physical activity trackers.
Exercise Program (Cohort B Rehab)
All HCT recipients 60 years and older will participate in a supervised exercise program from the time of discharge from HCT admission until day +100 post-HCT. Exercise compliance will be measured in part through physical activity trackers.
Locations (1)
Penn Medicine
Philadelphia, Pennsylvania, United States