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Leveraging Technology to Improve Medication Adherence in Youth With Kidney or Liver Transplant
Sponsor: Johns Hopkins University
Summary
Can the investigators create an effective way to improve adherence to immunosuppressant medication and reduce rejection, graft loss, and death in adolescents and young adults who have undergone kidney or liver transplantation? The investigators' mobile technology intervention uses real-time electronic pillbox-assessed dose timing and text message prompts to address antirejection medication nonadherence when nonadherence is detected.
Official title: Leveraging Technology to Improve Medication Adherence in Adolescent and Young Adult Kidney or Liver Transplant Recipients: A Micro-Randomized Trial
Key Details
Gender
All
Age Range
13 Years - 25 Years
Study Type
INTERVENTIONAL
Enrollment
65
Start Date
2024-03-19
Completion Date
2026-11-30
Last Updated
2025-04-16
Healthy Volunteers
No
Conditions
Interventions
mHealth Messaging Intervention Group
Participants will receive an electronic pill box; the research team will instruct participants on how to use this device. Participants will be asked to use the electronic pill box for their prescribed medicines for the duration of the study (up to 16 months). During the 12-week micro-randomized trial, participants will be randomized within person to receive (1) adherence support text messages or (2) no text message after each missed dose, and (1) praise text message or (2) no text message after each on time dose. Dose timing will be determined based on participant report of when they typically take their tacrolimus or sirolimus medicine.
Locations (1)
Johns Hopkins
Baltimore, Maryland, United States