Clinical Research Directory

Inclusion Criteria: 1. Males and females aged 6 months to 21 years of age; 2. Receiving care in the Victorian Paediatric Palliative Care Program for a non-oncological condition; 3. Pain, dystonia and/or gut dysfunction parent-rated symptom score above threshold, defined by rating on the relevant revised Memorial Symptom Assessment Scale (MSAS) question(s) of: 1. Frequency: "Frequently" or "Almost Constantly", AND 2. Severity: "Moderate", "Severe", or "Very Severe", AND 3. Distress: "Quite a bit", or "Very much"; 4. No changes in medication or other interventions in the two weeks prior to randomization; 5. Participant and family have the ability to comply with the protocol requirements, in the opinion of the investigator; 6. Agrees not to drive for the duration of the study. Exclusion Criteria: 1. Non-English speaking parents. 2. Participant history of psychosis, schizophrenia, bipolar disorder, or major depressive disorder, or a first degree family history of psychosis. 3. Taking medications which are known to interact with medicinal cannabis: warfarin, mTOR inhibitors (e.g sirolimus, tacrolimus), anti-cancer agents, citalopram \>20mg/day, escitalopram \>10mg/day. 4. Abnormal liver function tests defined as ALT \> 3 x ULN 5. Current use of illicit drugs or medicinal cannabis, or use in the 4 weeks prior to screening 6. Pregnant or intending to become pregnant during the study, or breastfeeding. 7. History of clinically significant suicidal thoughts in the prior 12 months. 8. Life expectancy less than 3 months in the opinion of the investigators 9. Allergy to any of the components in the investigatory products (eg sunflower oil) 10. Diagnosis of a malignant condition