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Effect of Nociception Level Monitoring During Remimazolam-based Total Intravenous Anesthesia on Intraoperative Opioid Requirements and Postoperative Pain
Sponsor: Yonsei University
Summary
This study aims to investigate whether the use of nociception monitoring during general anesthesia with remimazolam-based total intravenous anesthesia has an effect on intraoperative opioid requirements and postoperative pain. This study is a randomized trial with a 50% probability of being assigned to either group. Randomization will be done by an anesthesiologist not involved in anesthesia or postoperative outcome assessment. Patients and the investigator in charge of postoperative outcomes assessment will be blinded to group allocation.
Key Details
Gender
All
Age Range
19 Years - 64 Years
Study Type
INTERVENTIONAL
Enrollment
54
Start Date
2023-07-17
Completion Date
2025-11-21
Last Updated
2026-06-23
Healthy Volunteers
No
Interventions
Analgesia Nociception Index monitor
Patients will receive remimazolam-based total intravenous general anesthesia with nociception monitoring with the ANI monitor
Standard monitoring
Patients will receive remimazolam-based total intravenous general anesthesia based on hemodynamic monitoring and without nociception monitoring
Locations (1)
Yonsei University Health System, Severance Hospital
Seoul, South Korea