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A Combined Neurofeedback-TMS Intervention for Alcohol Use Disorder
Sponsor: Auburn University
Summary
The goal of this clinical study is to test the effectiveness of a supplemental fMRI neurofeedback and/or TMS intervention in individuals seeking treatment for Alcohol Use Disorder. After an initial visit, participants will come in once a week for four (4) weeks for an intervention session, which may or may not include TMS and MRI. Participants will be contacted for monthly follow-ups (remotely) for up to 12 months and will be asked to come in for two MRI follow-ups at 6 and 12 months.
Key Details
Gender
All
Age Range
19 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2025-10-01
Completion Date
2026-03-31
Last Updated
2025-10-07
Healthy Volunteers
No
Conditions
Interventions
Realtime fMRI Neurofeedback - Active
fMRI aided reinforcement of craving regulation
TMS - Active
rTMS to right dorsolateral prefrontal cortex to reduce craving
Realtime fMRI Neurofeedback - Yoked Sham
Display of feedback from other participant's sessions to serve as a sham for fMRI aided reinforcement of craving regulation
TMS - Sham
rTMS using placebo coil (no brain stimulation, emulates other features of active TMS), placed over right dorsolateral prefrontal cortex
Locations (1)
Auburn University
Auburn, Alabama, United States