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Impact of CErebral Endovascular PROcedures on the Systemic Immune responSe Response
Sponsor: University Hospital, Limoges
Summary
In our ICU, it could notice that patients with cerebral arterio-venous malformation (AVM) treated with embolization develop more severe Ventilator Associated Pneumoniae (VAP) compare to other patients hospitalized for neurological diseases. The Dimethylsulfoxyde (DMSO), the solvent of the embolization implant, is known to have immune effect on vitro analysis. The investigator want to prove that exposition to embolization implant for a cerebral AMV modify the cytokines production involved the system immune's regulation.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
78
Start Date
2022-12-05
Completion Date
2025-12-05
Last Updated
2024-04-05
Healthy Volunteers
No
Conditions
Interventions
Blood sample
Based on supplementary blood sampled before embolization procedure and 6 hours and 24 hours after we will be analyzed cytokines concentration (Elisa test) and cortisol
Locations (1)
Limoges University Hospital
Limoges, France