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NOT YET RECRUITING
NCT05623501
PHASE1

Phase I, Dose-Escalation Study of Dihydromyricetin (DHM) to Treat Alcohol-Associated Liver Disease

Sponsor: University of Southern California

View on ClinicalTrials.gov

Summary

The current proposal is designed as a first-in-human Phase 1 open-label, dose-escalation study to assess the safety, pharmacokinetics, and the maximum tolerated dose of DHM among healthy volunteers using a purified form of DHM from a local cGMP compliant source (Master Herbs, Inc).

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

12

Start Date

2024-09-15

Completion Date

2025-12-31

Last Updated

2024-09-03

Healthy Volunteers

Yes

Interventions

DRUG

Dihydromyricetin

Dose-escalation and lysine preparation

Locations (1)

University of Southern California

Los Angeles, California, United States