Clinical Research Directory

Inclusion Criteria: * Male or female, 18-85 years of age at the time of enrollment; * Anterior circulation ischemic stroke at least 6 months and up to 5 years prior to study enrollment; * Unilateral upper extremity hemiparesis as characterized by initial scores on upper limb subtest of the Fugl-Meyer Assessment (FMA-UE) between 20 and 45; * Intact cognitive function to understand the study procedures and goal setting (MMSE score above 23 and able to follow 3 step command); * Being familiar and comfortable with the use of a tablet or smartphone. Exclusion Criteria: * Severe spasticity (defined as a Modified Ashworth scale score of 3 or more) that would prevent safe performance of UE tasks; * Visual impairments as assessed by the NIH Stroke Scale Visual Field subscale (only subjects with no visual loss will participate in the study); or hemispatial neglect that would impair the subject ability to see feedback on the app screen (as assessed with the star cancellation test); * Individuals with open wounds or recent fracture (less than 3 months) in the UE, fragile skin or active infection as evaluated by the study therapist; * Individuals currently enrolled in a UE rehabilitation program (i.e., OT, research study) * Upper-extremity orthopedic injuries or severe pain resulting in movement limitations; * Diagnosis of other neurological disease (i.e., Parkinson's disease, multiple sclerosis, ...); * Severe proprioceptive deficits that impair the ability to process the vibration feedback, as assessed by physical examination during screening as assessed by the study therapist; * Not understanding spoken or written English; * Recent (less than 3 months) Botox injection in the UE or plan to undergo injections during the study timeline; * Contralateral motor deficits as assessed by clinical examination; * Brainstem and cerebellar stroke.