Clinical Research Directory
Browse clinical research sites, groups, and studies.
Does What You Eat Affect Your Brain
Sponsor: University of Washington
Summary
The purpose of this study is to use magnetic resonance imaging (MRI) to evaluate the human hypothalamus for signs of inflammation in response to specific diets. This research may lead to a better understanding of how poor nutritional quality may lead to obesity through effects on regions of the brain known to regulate body weight.
Official title: Assessing the Effect of Diet on Hypothalamic Gliosis in Humans
Key Details
Gender
All
Age Range
20 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
36
Start Date
2023-01-13
Completion Date
2025-06-30
Last Updated
2026-07-17
Healthy Volunteers
Yes
Interventions
Diet modification #1
Participants will be provided all meals for a 14-day period. For 7 of the days, meals will be 130% of estimated daily caloric needs and for the other 7 days, meals will be low in calories, consistent with recommendations for weight loss.
Diet modification #2
Participants will be provided all meals for a 14-day period. For 7 of the days, meals will be 150% of estimated daily caloric needs and for the other 7 days, meals will be meals will be low in calories, consistent with recommendations for weight loss.
Diet modification #3
Participants will be provided all meals for a 14-day period to be approximately 100% of estimated daily caloric needs.
Locations (1)
University of Washington
Seattle, Washington, United States