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RECRUITING
NCT05629000

Optimization Strategy of Carotid Artery Stenosis

Sponsor: Peking Union Medical College Hospital

View on ClinicalTrials.gov

Summary

The goal of this observational study is to learn about how to utilize multiple evaluation techniques in carotid artery stenosis patients for optimizing assessment of diagnosis and treatment strategy. The main questions it aims to answer are: * Identify best strategy that use multi-modal MRI and CT to assess patients' cerebral lesions and perfusion. * Identify best strategy that use multi-modal MRI, PET-MRI ultrasound and CT to assess components and characters of patients' carotid plaques. Participants will accept imaging examination before and after surgery. And doctors will collect basic characteristics, imaging results and biological samples of patients for analysis.

Official title: Cohort of Optimized Assessment Strategy of Carotid Artery Stenosis

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

1000

Start Date

2015-01-01

Completion Date

2026-12-31

Last Updated

2022-11-29

Healthy Volunteers

Yes

Interventions

PROCEDURE

Carotid revascularization

All patients received carotid revascularization surgery at Peking Union Medical College Hospital.

DIAGNOSTIC_TEST

MRI-PWI

Multi-modal MRI before and after surgery.

DIAGNOSTIC_TEST

CTA

CTA before and after surgery.

DIAGNOSTIC_TEST

PET/MRI

PET/MRI before surgery.

DIAGNOSTIC_TEST

Ultrasound

Ultrasound before and after surgery.

Locations (1)

vascular surgery department of PUMCH

Beijing, Beijing Municipality, China