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RECRUITING
NCT05629026
NA

Study of Lymphatic Dysfunction in Primary and Secondary Lymphedema

Sponsor: University Hospital, Toulouse

View on ClinicalTrials.gov

Summary

Lymphedema is a disorder of the lymphatic vascular system characterized by impaired lymphatic return and swelling of the extremities and accumulation of undrained interstitial fluid/lymph that results in fibrosis and adipose tissue deposition in the affected area. It can be an inherited condition (primary lymphedema) or occurs after cancer surgery and lymph node removal (secondary lymphedema). It causes a significant morbidity and is a common disabling disease affecting more than 200 million people worldwide, however there is no curative treatment for primary or secondary lymphedema.

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2024-02-21

Completion Date

2026-02

Last Updated

2025-12-31

Healthy Volunteers

No

Conditions

Interventions

PROCEDURE

Micro-biopsies

Two micro-biopsies of limb tissue will be carried out, one on the lymphedema and one in the upper limb not affected.

Locations (1)

Toulouse Hospital

Toulouse, France