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Study of Lymphatic Dysfunction in Primary and Secondary Lymphedema
Sponsor: University Hospital, Toulouse
Summary
Lymphedema is a disorder of the lymphatic vascular system characterized by impaired lymphatic return and swelling of the extremities and accumulation of undrained interstitial fluid/lymph that results in fibrosis and adipose tissue deposition in the affected area. It can be an inherited condition (primary lymphedema) or occurs after cancer surgery and lymph node removal (secondary lymphedema). It causes a significant morbidity and is a common disabling disease affecting more than 200 million people worldwide, however there is no curative treatment for primary or secondary lymphedema.
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2024-02-21
Completion Date
2026-02
Last Updated
2025-12-31
Healthy Volunteers
No
Conditions
Interventions
Micro-biopsies
Two micro-biopsies of limb tissue will be carried out, one on the lymphedema and one in the upper limb not affected.
Locations (1)
Toulouse Hospital
Toulouse, France