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Cancer Risk Assessment in Patients With a Constitutional Alteration of the PTEN Gene
Sponsor: Institut Bergonié
Summary
This is a multicentric, observational, retrospective and prospective study, aiming to estimate the risk of cancer occurrence in subjects carrying a PTEN mutation, based on the constitution of a national cohort.
Official title: National Cohort of Patients With Cowden's Disease and With a Constitutional Alteration of the PTEN Gene for the Prospective Assessment of the Risk of Cancer.
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
430
Start Date
2023-06-12
Completion Date
2048-01
Last Updated
2026-05-15
Healthy Volunteers
No
Conditions
Locations (45)
1-CHU Amiens
Amiens, France
2-CHU Angers
Angers, France
3-ICO Angers et Nantes
Angers, France
4-CHU Besançon
Besançon, France
5-CHU Bordeaux
Bordeaux, France
6-Institut Bergonié
Bordeaux, France
7-CHU Brest
Brest, France
8-Centre François Baclesse
Caen, France
9-CH Métropole Savoie Chambéry
Chambéry, France
10-CHU Colmar
Colmar, France
11-CHU Dijon
Dijon, France
12-CHU Grenoble
Grenoble, France
36-CH Le Mans
Le Mans, France
16-CHU Lille
Lille, France
17-CHU Limoges
Limoges, France
18a-Hospices Civils Lyon - Lyon Est
Lyon, France
18b-Hospices Civils Lyon - Lyon Sud
Lyon, France
19-AP-HM Hôpital de la Timone
Marseille, France
33-Institut Paoli Calmettes
Marseille, France
20-CHU Montpellier
Montpellier, France
21-CHU Nantes
Nantes, France
22-CHU Nice
Nice, France
32-Centre Antoine Lacassagne
Nice, France
37-CH Niort
Niort, France
23-CHU Nîmes
Nîmes, France
13a-AP-HP Hôpital Avicenne
Paris, France
13b-AP-HP Hôpital Saint-Antoine
Paris, France
13c-APH-HP Hôpital Salpétrière
Paris, France
13d-AP-HP Hôpital Trousseau
Paris, France
13e-AP-HP Hôpital Saint-Louis
Paris, France
13f-AP-HP Hôpital Robert Debré
Paris, France
14-Institut Curie
Paris, France
38-CHU Guadeloupe
Pointe à Pitre, France
24-CHU Poitiers
Poitiers, France
25-Institut du Cancer Courlancy
Reims, France
26-Centre Eugène Marquis
Rennes, France
27-CHU Rennes
Rennes, France
35-CHU Rouen
Rouen, France
28-CHU Saint-Etienne
Saint-Etienne, France
29-Institut Strauss
Strasbourg, France
30-CHU Toulouse
Toulouse, France
31-CHU Tours
Tours, France
40-CHU Troyes
Troyes, France
34-CH Valence
Valence, France
15-Institut Gustave Roussy
Villejuif, France