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Near Fatal Asthma in Children and Young People
Sponsor: University of Edinburgh
Summary
This study will report the frequency, risks factors, clinical care and estimate the future asthma risk of children and young people (aged 5-15 years) experiencing a Delphi defined near fatal asthma (NFA) attacks in the United Kingdom (UK) and Republic of Ireland (ROI). A greater understanding of the frequency and risk factors associated with NFA could help support children and young people (CYP), parents and clinicians to identify and modify risk, both independently and through a resulting clinical care pathway and also develop future research to improve effectiveness of interventions. The study will explore both commonly identified clinical factors, but also for the first time describe in detail the variance in medical management (acute and intensive care) that could lead to future clinical trials and guideline development to standardise care. The study will also describe, through data-linkage, socio-demographic factors associated with NFA, to include pollution, pollen, weather, viral prevalence that could lead to better care for higher risk CYP. To encourage more consistent, less fragmented care following a near fatal asthma attack, the study will consider how care is provided subsequent to an NFA attack using British Paediatric Surveillance Unit (BPSU) surveillance at 12 and 24 month follow up.
Key Details
Gender
All
Age Range
5 Years - 15 Years
Study Type
OBSERVATIONAL
Enrollment
400
Start Date
2022-10-31
Completion Date
2026-04-30
Last Updated
2025-06-27
Healthy Volunteers
Yes
Conditions
Interventions
Observational study
Observational surveillance study
Locations (1)
University of Edinburgh
Edinburgh, United Kingdom