Clinical Research Directory

Inclusion Criteria (patient) : * Patient is at least 18 years of age. * Patient having given informed consent * Patient with ALS who has already had at least two multidisciplinary assessments in the ALS center in Marseille with an evaluation by the clinical psychologist. * Patient with a motor handicap of grade 3 to 5 on the Rankin score * Patient with a primary family caregiver at home (spouse, child) willing to participate in the study * Patient who is a beneficiary of or affiliated with a social security plan Inclusion Criteria (caregiver) : * Adult subject at least 18 years of age. * Subject who has given informed consent. * Primary family caregiver of a patient with ALS who agrees to participate in the study * Caregiver present during hospital visits. Exclusion Criteria (patient): * Patients with a serious and unstable associated disease, cardiac, oncological, hepatic or renal, psychiatric (schizophrenia, bipolar) * Autonomous patient, who does not need the help of a third party for the basic gestures of daily life (Rankin 0 to 2) * Patient living in an institution or alone at home * Patient with cognitive impairment that interferes with activities of daily living * Patients with marked emotional lability (spasmodic crying) due to ALS * Patients who have had a recent diagnosis of their disease (less than 6 months) * Patients who are unaware of the severity of their condition * Any condition that in the opinion of the investigator or psychologist would not be compatible with the study. Exclusion Criteria (caregiver): * Subjects with severe and unstable cardiac, oncological, hepatic, renal or other illnesses. * Subject with a history of psychiatric illness