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The Effect of Eyeliner on Tear Composition, Tear Secretion and Tear Film Stability.
Sponsor: Zhongnan Hospital
Summary
Eyeliner is one of the most common eye cosmetics. The main ingredients are titanium oxide, pigment, grease and preservative. The user will apply the eyeliner to the eyelid and eyelash. With the blinking again and again, the components of the eyeliner may enter the tear film and continue to act on the eye surface. Therefore, the investigators suspect that the use of eyeliner may be an important factor leading to dry eye disease. In order to explore the relationship between the use of eyeliner and dry eye disease, the investigators plan to collect eye surface characteristic data of the two groups of people who use eyeliner and who do not use it.Then use Raman analysis to explore whether the use of eyeliner will lead to changes in tear composition.The investigators intend to analyze the difference of tear composition between the two groups to understand the relationship between the change of tear composition and tear film stability.So that the investigators can identify the risk factors of dry eye disease, and provide basis for prevention and early treatment.
Official title: The Effect of Eyeliner on Tear Composition, Tear Secretion and Tear Film Stability:a Prospective Cohort Study.
Key Details
Gender
FEMALE
Age Range
20 Years - 35 Years
Study Type
OBSERVATIONAL
Enrollment
80
Start Date
2022-11-20
Completion Date
2026-09-30
Last Updated
2025-09-29
Healthy Volunteers
Yes
Conditions
Interventions
no intervention
no intervention
Locations (1)
Zhongnan Hospital of Wuhan University
Wuhan, Hubei, China