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RECRUITING
NCT05632887

The Effect of Eyeliner on Tear Composition, Tear Secretion and Tear Film Stability.

Sponsor: Zhongnan Hospital

View on ClinicalTrials.gov

Summary

Eyeliner is one of the most common eye cosmetics. The main ingredients are titanium oxide, pigment, grease and preservative. The user will apply the eyeliner to the eyelid and eyelash. With the blinking again and again, the components of the eyeliner may enter the tear film and continue to act on the eye surface. Therefore, the investigators suspect that the use of eyeliner may be an important factor leading to dry eye disease. In order to explore the relationship between the use of eyeliner and dry eye disease, the investigators plan to collect eye surface characteristic data of the two groups of people who use eyeliner and who do not use it.Then use Raman analysis to explore whether the use of eyeliner will lead to changes in tear composition.The investigators intend to analyze the difference of tear composition between the two groups to understand the relationship between the change of tear composition and tear film stability.So that the investigators can identify the risk factors of dry eye disease, and provide basis for prevention and early treatment.

Official title: The Effect of Eyeliner on Tear Composition, Tear Secretion and Tear Film Stability:a Prospective Cohort Study.

Key Details

Gender

FEMALE

Age Range

20 Years - 35 Years

Study Type

OBSERVATIONAL

Enrollment

80

Start Date

2022-11-20

Completion Date

2026-09-30

Last Updated

2025-09-29

Healthy Volunteers

Yes

Conditions

Interventions

OTHER

no intervention

no intervention

Locations (1)

Zhongnan Hospital of Wuhan University

Wuhan, Hubei, China