Clinical Research Directory

Inclusion Criteria: 1. Age 30-75 years old; 2. No antihypertensive drugs were used and three blood pressure measurements were conducted on different days, with systolic blood pressure ≥ 140 mmHg (1 mmHg=0.133 kPa) and/or diastolic blood pressure ≥ 90 mmHg; or have a history of hypertension and are using antihypertensive drugs, even if the blood pressure is lower than 140/90 mmHg; 3. Left ventricular ejection fraction was normal (LVEF ≥ 0.5). 4. All patients agreed to participate in the experiment and signed the informed consent form. Exclusion Criteria: 1. Secondary hypertension caused by renal parenchymal diseases, renal vascular diseases, coarctation of aorta and endocrine system diseases; 2. Severe cardiovascular and cerebrovascular diseases; heart valve disease; persistent atrial fibrillation and severe arrhythmia; previously undergone cardiovascular disease surgery; 3. Abnormal liver function; abnormal renal function and diabetes; 4. Pregnant or breastfeeding women; 5. Expected survival time due to non-cardiovascular disease\<4 years; 6. Patients with poor echocardiographic image quality.