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RECRUITING
NCT05643859
NA

Impact of Dietary Fiber Supplementation on Colonic Microbiome

Sponsor: OHSU Knight Cancer Institute

View on ClinicalTrials.gov

Summary

This clinical trial tests whether daily fiber supplementation will change the mucosal microbiome of the colon. The microbiome are microorganisms that live in the human gut. They serve a vital role in maintaining health. Certain microbial strains are associated with the growth of colon polyps, which eventually could go on to form colon cancer. Giving dietary fiber supplements may help prevent precancerous polyps from ever developing.

Official title: Changes in Colonic Microbiome With Fiber Supplementation

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

120

Start Date

2023-04-01

Completion Date

2026-12-31

Last Updated

2026-01-15

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

Dietary Fiber

Given PO

PROCEDURE

Proctoscopy or anoscopy with Biopsy

Undergo proctoscopy or anoscopy

PROCEDURE

Colonoscopy

Undergo Colonoscopy

OTHER

Questionnaire Administration

Ancillary studies

Locations (1)

OHSU Knight Cancer Institute

Portland, Oregon, United States