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Impact of Dietary Fiber Supplementation on Colonic Microbiome
Sponsor: OHSU Knight Cancer Institute
Summary
This clinical trial tests whether daily fiber supplementation will change the mucosal microbiome of the colon. The microbiome are microorganisms that live in the human gut. They serve a vital role in maintaining health. Certain microbial strains are associated with the growth of colon polyps, which eventually could go on to form colon cancer. Giving dietary fiber supplements may help prevent precancerous polyps from ever developing.
Official title: Changes in Colonic Microbiome With Fiber Supplementation
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2023-04-01
Completion Date
2026-12-31
Last Updated
2026-01-15
Healthy Volunteers
No
Interventions
Dietary Fiber
Given PO
Proctoscopy or anoscopy with Biopsy
Undergo proctoscopy or anoscopy
Colonoscopy
Undergo Colonoscopy
Questionnaire Administration
Ancillary studies
Locations (1)
OHSU Knight Cancer Institute
Portland, Oregon, United States