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RECRUITING
NCT05649670
NA

Acute Stroke: Prehospital Versus In-HospitAL Initiation of Recanalization Therapy- ASPHALT

Sponsor: Centre Hospitalier St Anne

View on ClinicalTrials.gov

Summary

ASPHALT is an academic-driven open-label randomized controlled trial of Mobile Stroke Unit (MSU) deployment versus standard care in France, with blinded assessment of efficacy endpoints. 450 patients with confirmed acute ischemic stroke will be recruited over a 3-year period, with 3-month follow-up.

Official title: Prehospital Initiation of Reperfusion Therapy for Acute Ischemic Stroke: Randomized Medico-economic Evaluation of a Mobile Stroke Unit.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

450

Start Date

2023-10-16

Completion Date

2027-06-16

Last Updated

2024-02-01

Healthy Volunteers

No

Conditions

Interventions

OTHER

Mobile Stroke Unit deployment

Deployment of an MSU + conventional ambulance, allowing prehospital CT-scan imaging with intracranial CT angiography. This will allow prehospital intravenous thrombolysis and optimal triage (i.e. accurate identification of patients with large vessel occlusion, who are eligible for mechanical thrombectomy).

Locations (11)

AP-HP - hôpital Raymond Poincaré

Garches, France

AP-HP - hôpital Bicêtre

Le Kremlin-Bicêtre, France

AP-HP - hôpital Lariboisière

Paris, France

AP-HP - hôpital de la Pitié-Salpêtrière

Paris, France

GHU Paris psychiatrie & neurosciences

Paris, France

SAMU 75 de Paris

Paris, France

BSPP, Brigade des Sapeurs-Pompiers de Paris

Paris, France

AP-HP - hôpital Bichat - Claude-Bernard

Paris, France

Fondation Ophtalmologique Rothschild

Paris, France

Hôpital Saint Joseph

Paris, France

Hôpital Foch

Suresnes, France