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Vascular mEchanisms in, Stroke, dePression, dementiA, and deliRum: The VESPAR Project
Sponsor: University of Leicester
Summary
The goal of this observational study is to determine the feasibility of using integrated Transcranial Doppler Ultrasonography or Near Infrared Spectroscopy to detect changes in cerebral autoregulation and neurovascular coupling in healthy, stroke, dementia, depression and delirium populations. We also aim to: * Determine the optimal stimulus for neurovascular coupling * To derive sample size estimates for a future study * To develop a multilevel, multivariate model that can be applied to future datasets
Official title: Evaluating the Feasibility of Remote Haemodynamic Monitoring in a Cohort of Multi-ethnic Chronic Stroke Patients Using a Novel User Interface and Artificial Intelligence Algorithms
Key Details
Gender
All
Age Range
65 Years - Any
Study Type
OBSERVATIONAL
Enrollment
140
Start Date
2023-03-17
Completion Date
2026-08-26
Last Updated
2025-12-01
Healthy Volunteers
Yes
Locations (2)
University Hospitals of Leicester NHS Trust
Leicester, Leicestershire, United Kingdom
Leicestershire Partnership Trust
Leicester, Leicestershire, United Kingdom