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Seaweed-derived Rhamnan Sulfate and Vascular Function
Sponsor: University of Texas at Austin
Summary
The primary aim of the proposed investigation is to examine the hypothesis that a relatively short period of rhamnan sulfate supplementation would improve key markers of vascular dysfunction in middle-aged and older adults with at least one risk factors for cardiovascular disease.
Key Details
Gender
All
Age Range
35 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
15
Start Date
2023-04-01
Completion Date
2025-02-01
Last Updated
2026-06-09
Healthy Volunteers
Yes
Conditions
Interventions
Rhamnan sulfate
A randomized, placebo-controlled, double-blind crossover dietary supplement intervention consisting of 3 weeks each of rhamnan sulfate (Rhamnox100, Konan Chemical Manufacturing Co. LTD, Mie, Japan: 540 mg/day) or placebo with 2 weeks of washout between the interventions will be conducted. Dietary supplements (rhamnan sulfate) will be taken orally three time daily at each meal time. Rhamnan sulfate is a polysaccharide (carbohydrate) extracted from seaweeds and can be considered nutrition supplement. As each pill contains 90 mg of rhamnan sulfate or placebo, subjects will be taking 2 pills before or during each meal.
Locations (1)
Cardiovascular Aging Research Lab at UT Austin
Austin, Texas, United States