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RECRUITING
NCT05652088
NA

The Role of the Gastrointestinal-associated Lymphoid Tissue in the Cure of HIV Infection

Sponsor: Icahn School of Medicine at Mount Sinai

View on ClinicalTrials.gov

Summary

The objective of this study is to understand the effects of HIV cure strategies on the virus and immune cells that reside within the gastrointestinal tract. Subjects receiving therapies with the potential for HIV cure will undergo a colonoscopy to obtain gastrointestinal tissue for research assays. This study will test whether receiving these therapies will induce changes in the immune cells in the gastrointestinal tract and reduce the tissue-associated HIV viral levels.

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

10

Start Date

2023-06-30

Completion Date

2026-06

Last Updated

2025-07-04

Healthy Volunteers

No

Conditions

Interventions

PROCEDURE

Colonoscopy

Colonoscopy is a procedure where an instrument called colonoscope is inserted through the rectum to look at the entire internal surface of the intestine. Participants will be placed on a stretcher on the left side. A colonoscope will be advanced into the colon and into the terminal ileum. The entire procedure should take approximately 40 minutes

Locations (1)

Icahn School of Medicine at Mount Sinai

New York, New York, United States