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The Role of the Gastrointestinal-associated Lymphoid Tissue in the Cure of HIV Infection
Sponsor: Icahn School of Medicine at Mount Sinai
Summary
The objective of this study is to understand the effects of HIV cure strategies on the virus and immune cells that reside within the gastrointestinal tract. Subjects receiving therapies with the potential for HIV cure will undergo a colonoscopy to obtain gastrointestinal tissue for research assays. This study will test whether receiving these therapies will induce changes in the immune cells in the gastrointestinal tract and reduce the tissue-associated HIV viral levels.
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
10
Start Date
2023-06-30
Completion Date
2026-06
Last Updated
2025-07-04
Healthy Volunteers
No
Conditions
Interventions
Colonoscopy
Colonoscopy is a procedure where an instrument called colonoscope is inserted through the rectum to look at the entire internal surface of the intestine. Participants will be placed on a stretcher on the left side. A colonoscope will be advanced into the colon and into the terminal ileum. The entire procedure should take approximately 40 minutes
Locations (1)
Icahn School of Medicine at Mount Sinai
New York, New York, United States