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Does Joint Lavage Reduce Intraarticular Inflammation in High-energy Tibial Pilon Fractures?
Sponsor: United States Naval Medical Center, San Diego
Summary
High-energy tibial pilon fractures have historically been associated with poor outcomes largely due to the elevated risk of severe post-traumatic arthritis. Intraarticular fractures result in a pro-inflammatory hemarthrosis that may further exacerbate the chondral damage that was sustained due to the original injury. This project will study the effect of joint lavage on the concentration of inflammatory cytokines in the ankle following a high-energy tibial pilon fracture and the resultant effect on short-term patient outcomes.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2023-01-15
Completion Date
2025-07
Last Updated
2024-05-06
Healthy Volunteers
Yes
Interventions
Joint Lavage
An arthrotomy will be made at the time of temporary external fixation and 1L normal saline will be used to irrigate the ankle joint.
Locations (1)
Brooke Army Medical Center
Fort Sam Houston, Texas, United States