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Safety, Feasibility, and Tolerability of Sulforaphane in Children with Chronic Kidney Disease
Sponsor: University of Rochester
Summary
This purpose of this study is to investigate potential new therapeutics in pediatric chronic kidney disease (CKD). The specific aims are to identify safe dosing and tolerability of sulforaphane (SFN) supplementation in children with moderate and advanced CKD. Secondary objectives will include preliminary exploration of changes in oxidative and inflammatory biomarkers in response to SFN supplementation in this population.
Official title: Safety, Feasibility, and Tolerability of Sulforaphane in Children with CKD
Key Details
Gender
All
Age Range
1 Year - 17 Years
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2023-05-15
Completion Date
2025-12-31
Last Updated
2024-09-19
Healthy Volunteers
No
Conditions
Interventions
Sulforaphane
Dosing study one to four 30 mg/d tablets depending on weight
Locations (1)
University of Rochester Medical Center
Rochester, New York, United States