Clinical Research Directory

Inclusion Criteria: 1. Patient admitted from Jan. 1st 2023 to Jan. 1st 2025; 2. Age ≥ 18; 3. Intracranial atherosclerosis stenosis measured as ≥70% by digital subtraction angiography or by other noninvasive methods, such as transcranial doppler, computed tomography angiography, or magnetic resonance angiography; 4. A history of stroke/transient ischemic attack attributed to ICAS; 5. Verbal and written informed consent is provided at the time of admission by patients or their legally authorized representatives. Exclusion Criteria: 1. Stenosis of other causes; 2. Prior ipsilateral stroke with residual deficits; 3. Uncontrolled hypertension (defined as systolic blood pressure ≥200 mm Hg despite medications at enrollment); 4. Peripheral vascular disease (especially subclavian arterial and upper limb artery stenosis or occlusion).