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RECRUITING
NCT05657990
EARLY_PHASE1

Post Operative Urinary Retention (POUR) Following Thoracic Oncological Surgery

Sponsor: Hackensack Meridian Health

View on ClinicalTrials.gov

Summary

This is a feasibility study looking at whether the use of Tamsulosin could lower the high incidence of postoperative urinary retention (POUR) in older men who undergo an oncological thoracic surgical procedure for suspected or confirmed cancer. In addition, the study will try to identify the time of resumption of presurgical urinary function post Tamsulosin administration.

Key Details

Gender

MALE

Age Range

55 Years - Any

Study Type

INTERVENTIONAL

Enrollment

46

Start Date

2023-04-03

Completion Date

2026-12

Last Updated

2026-02-10

Healthy Volunteers

No

Interventions

DRUG

Tamsulosin

Tamsulosin 0.4 mg one time daily after a meal for seven days prior to surgery. Post-surgery, an ultrasound of the bladder will be completed approximately six hours after surgery to assess the bladder. If the bladder ultrasound shows more than 400 cc of urine in the bladder, or if the study subject passes urine on his own and there is more than 100cc or less than 400 cc of urine left in the bladder, he will be encouraged to try to pass urine. Study subject will be monitored for two additional hours. If a study subject is unable to pass urine at this time or the bladder has 400 cc or more of urine left in it, he will have an intermittent catheter (in and out) to drain urine. If the bladder has greater than 500 cc (which is approximately 16 and two-thirds ounces) per catheterization for more than 24 hours, and the study subject cannot pass urine, an indwelling catheter may be considered.

Locations (4)

Ocean University Medical Center

Brick, New Jersey, United States

South Ocean University Medical Center

Manahawkin, New Jersey, United States

Jersey Shore University Medical Center

Neptune City, New Jersey, United States

Riverview Medical Center

Red Bank, New Jersey, United States