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RECRUITING
NCT05663840
NA

Effects of Exercise on Dystonia Pathophysiology

Sponsor: University of Florida

View on ClinicalTrials.gov

Summary

The purpose of this research study is to investigate how the brain and motor behavior changes in individuals with dystonia in response to exercise training.

Official title: Progressive Resistance Exercise and Dystonia Pathophysiology.

Key Details

Gender

All

Age Range

30 Years - 85 Years

Study Type

INTERVENTIONAL

Enrollment

56

Start Date

2022-10-13

Completion Date

2027-12-31

Last Updated

2025-07-28

Healthy Volunteers

No

Conditions

Interventions

BEHAVIORAL

Progressive resistance exercise

Patients with predominant symptoms of cervical dystonia will receive exercise training. Patients will receive progressive resistance exercise focused cervical and shoulder training (PERFECT) plus standard-of-care (SOC) therapy. Resistance training will consist of mainly muscle-strengthening exercises for the neck, shoulder and arms and a few upper trunk muscles. Resistance training will be guided by physical therapists at twice a week schedule for 6 months. These participants will also receive SOC therapy.

BEHAVIORAL

Standard of care

Subjects will receive SOC therapy only

Locations (1)

University of Florida

Gainesville, Florida, United States