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Effects of Exercise on Dystonia Pathophysiology
Sponsor: University of Florida
Summary
The purpose of this research study is to investigate how the brain and motor behavior changes in individuals with dystonia in response to exercise training.
Official title: Progressive Resistance Exercise and Dystonia Pathophysiology.
Key Details
Gender
All
Age Range
30 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
56
Start Date
2022-10-13
Completion Date
2027-12-31
Last Updated
2025-07-28
Healthy Volunteers
No
Conditions
Interventions
Progressive resistance exercise
Patients with predominant symptoms of cervical dystonia will receive exercise training. Patients will receive progressive resistance exercise focused cervical and shoulder training (PERFECT) plus standard-of-care (SOC) therapy. Resistance training will consist of mainly muscle-strengthening exercises for the neck, shoulder and arms and a few upper trunk muscles. Resistance training will be guided by physical therapists at twice a week schedule for 6 months. These participants will also receive SOC therapy.
Standard of care
Subjects will receive SOC therapy only
Locations (1)
University of Florida
Gainesville, Florida, United States