Clinical Research Directory
Browse clinical research sites, groups, and studies.
Effects of Multiple Mega-dose of Vitamin D3 Supplementation on Ameliorating Moderate to Severe Chronic Pain in Hemodialysis Patients
Sponsor: Taipei Medical University Hospital
Summary
Pain is a major complaint in hemodialysis (HD) patients. Concentrations of parathyroid hormone (PTH) \>250 pg/ml are associated with chronic pain. Visual Analogue Scale (VAS) score which is used to assess the pain severity is positively related to PTH levels. This study is aimed to assess the effects of multiple mega dosages vitamin D supplementations in HD patients with chronic pain. It's a single-center, parallel, double-blind randomized control trial that administrations of 576,000 IU once a week of vitamin D3 for 4 weeks or placebo are for 120 eligible subjects. VAS and laboratory tests including serum concentrations of 25(OH)D, calcium, phosphorus, PTH and C-reactive protein will be evaluated.
Key Details
Gender
All
Age Range
20 Years - Any
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2023-03-15
Completion Date
2027-12-31
Last Updated
2023-03-30
Healthy Volunteers
No
Interventions
Vitamin D
Oral supplementaiton of 576,000 IU once a week of vitamin D3 for 4 weeks
Placebo
Oral supplementaiton of placebo once a week for 4 weeks
Locations (1)
Taipei Medical University Hospital
Taipei, Taiwan