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RECRUITING
NCT05667805
PHASE4

Coagulation in Cirrhosis

Sponsor: Medical University of Vienna

View on ClinicalTrials.gov

Summary

Out of fear of bleeding, liver cirrhosis patients are often treated prophylactically with blood and coagulation products before minor interventions. The COUCH study will examine whether these patients benefit from a restrictive administration of coagulation products.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

400

Start Date

2023-01-19

Completion Date

2027-03-01

Last Updated

2025-01-14

Healthy Volunteers

No

Conditions

Interventions

DRUG

Platelet Concentrate

Liberal use (standard treatment)

DRUG

Prothrombin Complex Concentrate

Liberal use (standard treatment)

OTHER

Restricitve Use

Restrictive use of human prothrombin complex and platelet concentrates. No prophylactic substitution.

Locations (1)

General Hospital of the Medical University of Vienna

Vienna, Austria