Clinical Research Directory

Inclusion Criteria: * Patient over 18 years of age * Patient who has read and signed the consent form for participation in the study * Patient candidate for ERCP with virgin papilla Exclusion Criteria: * Patient with sphincterotomized papilla * Patient under court protection, guardianship or curatorship * Pregnant woman or woman of childbearing age without highly effective contraception for the duration of the study (surgically sterile, intrauterine device (\> 14 days), hormonal contraception (same dose and formulation for at least 6 months), sexual abstinence. Women after menarche and until they become postmenopausal, unless they are permanently infertile or have undergone surgical sterilization, are considered to be of childbearing age, i.e. fertile. A postmenopausal condition is defined as the absence of menstruation for 12 months without any other medical cause * Patient not affiliated with the French social security system * Patient participating in another clinical research protocol * Impossibility to give the subject informed information and/or written informed consent: dementia, psychosis, disorders of consciousness, non-French speaking patient * Contraindication to the use of NSAIDs * Contraindication to anesthesia or to the administration of any of the products used in anesthesia protocols (including lidocaine)