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A Study of Pressure Waveform Analysis in Coronary Artery-II
Sponsor: National Taiwan University Hospital Hsin-Chu Branch
Summary
The goal of this observational study is to test the feasibility of intracoronary adenosine administration during coronary flow reserve(CFR) and index of microcirculatory resistance(IMR) assessment in a population with angina. The main questions it aims to answer are: * Repeatability of CFR and IMR assessment while hyperemia with intracoronary adenosine was administered. * Evaluate the correlation of the intrinsic signal of coronary waveform versus physiologic ischemia, while defined by fractional flow reserve(FFR) and CFR respectively. * The predictive value of FFR, CFR, and IMR on major adverse cardiovascular outcomes in 3 years Participants will undergo FFR, CFR, and IMR assessments in the catheterization laboratory of the National Taiwan University Hospital Hsin-Chu Branch, then clinical events follow up for 3 years.
Key Details
Gender
All
Age Range
21 Years - Any
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2023-01-04
Completion Date
2027-12-31
Last Updated
2023-01-05
Healthy Volunteers
No
Conditions
Interventions
CFR and IMR group
Participants will undergo repeat intracoronary adenosine administration during CFR and IMR measurement
Locations (1)
National Taiwan University Hospital Hsin-Chu branch
Hsinchu, Taiwan