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PRP for Glenohumeral Osteoarthritis
Sponsor: Hospital for Special Surgery, New York
Summary
The glenohumeral joint is the third most common large joint to be affected by OA. Conservative treatments include physical activity, corticosteroid injections, and medications. PRP is an emerging treatment that has shown efficacy in different musculoskeletal conditions. The use of PRP for glenohumeral OA has been described sparingly in the literature but has shown efficacy in a couple studies and case reports. However, all of the previous studies investigating PRP for glenohumeral OA have focused on low-dose PRP preparations (\~3X), and none have compared PRP treatment to saline treatment. This study aims to compare outcomes following single injections of low-dose PRP, high-dose PRP, or saline in patients with glenohumeral osteoarthritis.
Official title: Outcomes Following Single Injections of Low-dose Platelet-rich Plasma (PRP), High-dose PRP, or Saline in Patients With Glenohumeral OA: a Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
INTERVENTIONAL
Enrollment
135
Start Date
2023-05-02
Completion Date
2026-09-01
Last Updated
2025-10-06
Healthy Volunteers
No
Conditions
Interventions
Low-dose PRP
Injection
High-dose PRP
Injection
Saline
Injection
Locations (1)
Hospital for Special Surgery
New York, New York, United States