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RECRUITING
NCT05675527
PHASE4

PRP for Glenohumeral Osteoarthritis

Sponsor: Hospital for Special Surgery, New York

View on ClinicalTrials.gov

Summary

The glenohumeral joint is the third most common large joint to be affected by OA. Conservative treatments include physical activity, corticosteroid injections, and medications. PRP is an emerging treatment that has shown efficacy in different musculoskeletal conditions. The use of PRP for glenohumeral OA has been described sparingly in the literature but has shown efficacy in a couple studies and case reports. However, all of the previous studies investigating PRP for glenohumeral OA have focused on low-dose PRP preparations (\~3X), and none have compared PRP treatment to saline treatment. This study aims to compare outcomes following single injections of low-dose PRP, high-dose PRP, or saline in patients with glenohumeral osteoarthritis.

Official title: Outcomes Following Single Injections of Low-dose Platelet-rich Plasma (PRP), High-dose PRP, or Saline in Patients With Glenohumeral OA: a Randomized Controlled Trial

Key Details

Gender

All

Age Range

18 Years - 100 Years

Study Type

INTERVENTIONAL

Enrollment

135

Start Date

2023-05-02

Completion Date

2026-09-01

Last Updated

2025-10-06

Healthy Volunteers

No

Interventions

BIOLOGICAL

Low-dose PRP

Injection

BIOLOGICAL

High-dose PRP

Injection

OTHER

Saline

Injection

Locations (1)

Hospital for Special Surgery

New York, New York, United States