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Perioperative Immunonutrition Intervention and Oral Decontamination in Elderly Surgical Patients
Sponsor: Huang YuGuang
Summary
Elderly patients are vulnerable to postoperative complications. Preoperative malnutrition and poor oral hygiene are risk factors for postoperative complications especially pulmonary complications. This study aims to investigate the feasibility and efficacy of perioperative oral decontamination and immunonutrition supplement on reducing postoperative complications in elderly surgical patients.
Official title: Effect of Perioperative Immunonutrition Intervention and Oral Decontamination on Postoperative Complications in Elderly: a Prospective Randomized Controlled Trial
Key Details
Gender
All
Age Range
65 Years - Any
Study Type
INTERVENTIONAL
Enrollment
590
Start Date
2023-02-06
Completion Date
2026-01-01
Last Updated
2025-03-03
Healthy Volunteers
No
Conditions
Interventions
immunonutrition
Patients in the intervention group will receive additional immunonutrition supplementation, which is oral intake of ORAL IMPACT™ 2 servings per day from the day of allocation at the preoperative anesthesia clinic until the day before surgery.
oral chlorhexidine decontamination
Patients in the intervention group will receive oral chlorhexidine decontamination using 0.12% chlorhexidine oral rinse twice daily from the day before surgery until postoperative day 3.
Locations (1)
Peking Union Medical College Hospital
Beijing, China