Clinical Research Directory

Inclusion Criteria: * Breast cancer patient aged \>18 years old * Breast cancer patient with clinically ALNs metastases (cN1 or cN2). * Breast cancer patient with no clinical metastasis and tumor size ≥5cm or no sentinel lymph node biopsy facility in the hospital. * Any breast cancer patients that receive neoadjuvant systemic therapy. Exclusion Criteria: * Stage IV breast cancer patients who do not show clinical and radiological improvement after primary systemic therapy. * Breast cancer patients with previous surgeries such as mastectomy, axillary lymph node biopsy, sentinel lymph node biopsy (SLNB), and ALND. * Breast cancer patients with prior breast, chest wall, axillary, or neck radiotherapy. * Breast cancer patients with preoperative lymphatic system abnormality detected by ICG lymphography. * Breast cancer patients with iodine allergy, asthma, decreased kidney function, pregnancy, and lactation.