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RECRUITING
NCT05683093

Cardiovascular Longitudinal ALSPAC Research Investigations Following Hypertensive Pregnancy in Young Adulthood

Sponsor: University of Oxford

View on ClinicalTrials.gov

Summary

The purpose of this study is to understand more about why young people who were born to a hypertensive pregnancy may have increased risk of high blood pressure and are often at increased risk of heart and blood vessel disease later in life.

Official title: Cardiovascular Longitudinal the Avon Longitudinal Study of Parents and Children (ALSPAC) Research Investigations Following Hypertensive Pregnancy in Young Adulthood

Key Details

Gender

All

Age Range

30 Years - 40 Years

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2022-11-17

Completion Date

2027-01-31

Last Updated

2023-01-12

Healthy Volunteers

No

Interventions

OTHER

History of being born to hypertensive or normal pregnancy

CLARITY is an observational study whereby participants will attend one 4-hr visit the Division of Cardiovascular Medicine, University of Oxford at the John Radcliffe Hospital in Oxford, with the option to split the study visit over two days for convenience. Participants will be invited by the ALSPAC study team to attend a study visit in Oxford where the investigators will use MRI and other imaging modalities to study the brain, heart, liver, kidneys, and vasculature using standardised protocols. A dataset including information from previous follow-up of these cohorts and the detailed pregnancy data available within ALSPAC will be generated by the study team in Bristol and integrated with available data from the Oxford cohorts.

Locations (1)

University of Oxford

Oxford, Oxfordshire, United Kingdom